top of page
IMG_2497_edited.jpg

The Donnelly lab is in the department of Neurobiology at the University of Pittsburgh School of Medicine and a member of the LiveLikeLou Center for ALS Research in the University of Pittsburgh Brain Institute. We study the biology underlying neurodegenerative diseases with a particular interest in understanding neuronal death observed in Amyotrophic Lateral Sclerosis (ALS), and Frontotemporal Dementia (FTD). A feature of neurodegenerative diseases is intracellular protein inclusions or clumping. One area of interest is understanding the molecular triggers that initiate inclusion formation and to identify ways to stop these from forming. In addition, we are interested in understanding genetic causes that contribute to these diseases. The ultimate goal of our work is to uncover biological mechanisms that might be targeted to slow or stop these fatal disorders.    

ABOUT

LATEST NEWS
OUR PARTNERS
LIVE LIKE LOU
Live like lou_edited.jpg
MDA-ALS CLINIC
Pitt Logo.png
DONUT DASH
Donut Dast.png
BRAIN INSTITUTE
Pitt Logo.png
PIND
PIND_edited.png
DEPARTMENT
OF NEUROBIOLOGY
Pitt Logo.png
NEALS
neals.jpeg
PROTEIN CONFORMATIONAL DISEASES
Pitt Logo.png
bottom of page